The 21st TSC was established on October 18, 2000. After the fall of the Berlin Wall and the diminishment of threat from the Soviet east, the mission of the command changed drastically. The mission set was no longer to prepare for major conflict in theater; rather, it was to support numerous ongoing operations within theater and in neighboring theaters.
During this time, the 21st TSC was providing a significant amount of direct support to combat units in theater. The deactivation of the Army Corps Support Commands put the mission of direct support to combat units in the 21st TSC's hands. This change also reflected the fact that the unit now commanded deployable forces and was considered a forward deployed command.
Direct support to combat units and the command and control of deployable forces made the 21st TSC a very different command than its predecessors.